Wegovy Pill(Oral Semaglutide)
The first oral GLP-1 approved for weight loss. Clinically proven 16.6% average weight loss — no injections, no refrigeration.
From £99 per month
Key Features
16.6% Avg.
Weight Loss in 64 Weeks
Daily Pill
No Needles Required
No Fridge
Room Temperature Storage
MHRA Licensed
UK Approved 2026
What Is the Wegovy Pill?
A once-daily oral GLP-1 medication for weight management — the same active ingredient as injectable Wegovy, in a convenient tablet.
Same Science, No Needle
Contains semaglutide, the same active ingredient as injectable Wegovy. Formulated with SNAC technology — a protective molecule that shields the medication through your stomach for effective oral absorption.
Appetite Regulation
Mimics GLP-1, a naturally-occurring hormone released after eating. Signals fullness, reduces hunger, and helps you make informed decisions about food.
Slows Gastric Emptying
Delays how quickly food moves through your stomach, keeping you fuller for longer and encouraging smaller portion sizes naturally.
Targets Stored Fat
Helps your body burn fat more efficiently by targeting stored fat rather than muscle, supporting sustainable, healthy weight loss.
How to Take It
Morning, Empty Stomach
Take once daily first thing in the morning before eating or drinking.
Small Sip of Water
Swallow whole with up to 120ml of plain water only. Do not crush or chew.
Wait 30 Minutes
Wait at least 30 minutes before eating, drinking, or taking other medications.
No Refrigeration
Store at room temperature below 30°C. No fridge needed — easy for travel and everyday life.
Do Not
- Crush, cut, chew, or dissolve
- Take more than 1 tablet per day
- Use any liquid other than water
- Store outside original packaging
Missed a Dose?
Skip the missed dose and take your next tablet the following morning as normal. Do not double up.
Storage Tips
Room temperature, cool and dry. Keep in original packaging. No fridge needed — unlike injectable Wegovy.
Tips for Success
Set a Reminder
Same time every morning using your phone alarm.
Keep It Bedside
Bottle + water glass on your bedside table.
Morning Routine
Pair it with waking up or brushing your teeth.
Track Progress
Weekly weigh-ins help you and your prescriber.
Clinical Results
OASIS 1 Trial
Phase 3, randomised, double-blind — 667 participants over 64 weeks
- 16.6% average body weight reduction over 64 weeks — roughly 16.6 kg for someone weighing 100 kg
- Comparable efficacy to injectable Wegovy — same active ingredient, oral delivery
- 4.5× more weight loss than lifestyle changes alone (placebo group lost just 1.9%)
OASIS 4 Trial
Longer-term study — participants followed for 71 weeks
- Approximately 14–17% body weight loss over 71 weeks, confirming sustained long-term efficacy
- 1 in 4 participants achieved 20%+ weight loss — exceptional results for an oral medication
- Improvements beyond weight — reduced waist circumference, improved blood sugar levels, and better cardiovascular markers
- MHRA approved 11 June 2026 — the UK was the first country in Europe to approve oral semaglutide for weight management
Results from the OASIS clinical programme (oral semaglutide 25 mg vs placebo). Individual results vary depending on adherence, metabolism, and other factors. All participants received lifestyle counselling alongside medication.
Pricing
Transparent, all-inclusive monthly pricing. Includes medication, prescriber review, and ongoing clinical support.
Weeks 1–4
£99
per month (30 tablets)
1.5mg
Starting dose
Weeks 5–8
£136
per month (30 tablets)
4mg
First increase
Weeks 9–12
£143
per month (30 tablets)
9mg
Second increase
Week 13+
£170.10
per month (30 tablets)
25mg
Maintenance dose
Prescription subject to clinical suitability. Dose escalation schedule may vary based on your prescriber's recommendation.
Pill vs Injection: How They Compare
Both deliver semaglutide with comparable weight loss results. Choose the format that fits your lifestyle.
| Feature | Wegovy Pill | Wegovy Injection |
|---|---|---|
| Active Ingredient | Semaglutide | Semaglutide |
| Administration | Daily oral tablet | Weekly injection |
| Average Weight Loss | 16.6% (64 weeks) | Up to 21% (68 weeks) |
| Needle-Free | ✓ Yes | ✗ No |
| Refrigeration | Not required | Required (2–8°C) |
| Dose Escalation | 1.5mg → 25mg (17 weeks) | 0.25mg → 2.4mg (16 weeks) |
| MHRA Approved | 2026 | 2021 |
| Starting Price | From £99/month | From £175/month |
Compare All Treatments
See how the Wegovy Pill stacks up against all available weight loss medications.
| Treatment | Weight Loss | Frequency | Method | Refrigeration | Best For | From |
|---|---|---|---|---|---|---|
| Wegovy PillNEW | 16.6% | Daily | Oral tablet | No | Needle-free GLP-1 weight loss | £99 |
| Mounjaro | Up to 23% | Weekly | Injection | Yes | Dual-action (GLP-1 + GIP) | £199 |
| Wegovy Injection | Up to 21% | Weekly | Injection | Yes | Cardiovascular benefits | £175 |
| Saxenda | Up to 10% | Daily | Injection | Yes | Consistent daily routine | £149 |
| Orlistat | Up to 8% | 3× daily | Oral capsule | No | Fat absorption blocker | £49 |
Dose Escalation Schedule
Your dose is gradually increased over approximately 17 weeks. This allows your body to adjust and helps minimise side effects.
Weeks 1–4: 1.5mg daily
Starting dose
£99/mo
Weeks 5–8: 4mg daily
First increase
£136/mo
Weeks 9–12: 9mg daily
Second increase
£143/mo
Week 13+: 25mg daily
Maintenance dose
£170.10/mo
Side Effects & Safety Information
Common Side Effects
Most side effects are mild and typically improve as your body adjusts:
- Nausea
- Reduced appetite
- Constipation
- Diarrhoea
- Vomiting
- Bloating
- Stomach discomfort
- Fatigue
- Headache
- Hair thinning
When to Seek Medical Attention
- • Severe stomach pain that will not go away
- • Vision changes or severe eye pain
- • Rapid heartbeat or palpitations
- • Symptoms of pancreatitis
- • Signs of allergic reaction (rash, swelling, breathing difficulty)
- • Difficulty swallowing or persistent throat pain
Who Is Eligible?
You May Be Eligible If
- Your BMI is 30 or above
- Your BMI is 27+ with a weight-related condition (e.g., high blood pressure, high cholesterol, pre-diabetes)
- You are 18 years or older
- You prefer a needle-free treatment option
Not Suitable If
- You are pregnant or breastfeeding
- You have a personal or family history of medullary thyroid carcinoma
- You have Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
- You have a history of pancreatitis
- You have difficulty swallowing tablets
Frequently Asked Questions
Explore Related Resources
Wegovy Weight Loss Guide
Complete guide to Wegovy including dosing, results, and what to expect.
Wegovy Injection
Compare with the weekly injectable Wegovy pen for weight management.
NAD⁺ Injection Pen
Support your energy levels with NAD⁺ therapy alongside your GLP-1 treatment.
Compare treatments: Mounjaro · Wegovy Injection · Saxenda · Orlistat
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