Mounjaro (Tirzepatide)Dual-Action Weekly Injection
Mounjaro's dual GLP-1 and GIP action achieved up to 22.5% body weight reduction in the SURMOUNT-1 clinical trial. A prescriber will assess whether this treatment is suitable for you. Individual results may vary.
What is Mounjaro?
Mounjaro is a prescription-only medication manufactured by Eli Lilly for weight management and Type 2 diabetes. It's a once-weekly subcutaneous (under the skin) injection that contains the active ingredient tirzepatide.
What makes Mounjaro unique is that it mimics two important gut hormones: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These hormones work together to reduce appetite, help you feel fuller for longer, slow stomach emptying, and improve blood sugar control.
This dual mechanism makes Mounjaro different from other weight loss injections like Wegovy, which only target the single hormone GLP-1. Clinical trials have consistently shown that Mounjaro delivers more significant weight loss results than single-action GLP-1 medications.
MHRA Approved for Weight Loss
Mounjaro was originally approved for treating Type 2 diabetes. In November 2023, the Medicines and Healthcare products Regulatory Agency (MHRA) extended its licence to include weight management for adults aged 18 and over, making it one of only a few prescription weight loss treatments officially approved by UK regulators.
How Does Mounjaro Work?
Mounjaro works by mimicking two naturally occurring gut hormones that regulate appetite, blood sugar, and metabolism. Understanding how these hormones work helps explain why Mounjaro is so effective.
Glucagon-Like Peptide-1
GLP-1 is a hormone your gut releases after eating. It plays a key role in controlling appetite and blood sugar.
- Slows stomach emptying, helping meals feel more satisfying and keeping you fuller for longer
- Sends signals to the brain that reduce appetite and curb cravings
- Boosts insulin release and suppresses glucagon to help keep blood sugar steady
Glucose-Dependent Insulinotropic Polypeptide
GIP is another gut hormone that works alongside GLP-1 to regulate metabolism and appetite.
- Helps the body use insulin more effectively after meals, allowing blood sugar levels to settle smoothly
- In the brain, GIP signals can dampen appetite, making it easier to feel satisfied with smaller portions
- Enhances the effects of GLP-1 for more powerful weight loss results
The Dual-Action Advantage
Mounjaro is currently the only licensed weight loss medicine that activates both the GLP-1 and GIP receptors. This dual mechanism is why clinical trials consistently show Mounjaro delivers more significant weight loss than single-action GLP-1 medications.
What Results Can You Expect?
Mounjaro has demonstrated significant weight loss results in clinical trials (SURMOUNT programme). Individual results may vary depending on adherence and other factors.
Average body weight loss at highest dose
SURMOUNT-1 trial: 72 weeks on 15mg tirzepatide
Lost at least 5% body weight
Clinically meaningful weight loss threshold
Lost at least 20% body weight
Significant weight loss in clinical trials
TLWLC Results Go Further
Our patients average 21.55% total body weight loss—53% more than medication alone—thanks to our comprehensive programme combining Mounjaro with personalised nutrition and lifestyle coaching.
Your Weight Loss Timeline
Weeks 1-4 (2.5mg)
Starting dose. Appetite reduction begins within days. You may notice less "food noise" and reduced cravings.
Weeks 5-12 (5mg-7.5mg)
Steady weight loss of 1-2 lbs per week as dose increases. Most side effects settle.
Months 3-6 (10mg+)
Significant visible changes. Weight loss typically 12-18% of starting weight. Health markers improving.
12+ Months (15mg)
Maximum weight loss achieved. Most patients reach 20%+ reduction. Focus shifts to maintenance.
Who Is Mounjaro For?
You May Be Eligible If:
- Your BMI is 30 or higher (obesity)
- Your BMI is 27+ with weight-related conditions (diabetes, high blood pressure, high cholesterol)
- You're aged 18 or over
- Previous weight loss attempts haven't worked long-term
- You want the most effective weight loss medication available
Mounjaro May Not Be Suitable If:
- You have a personal or family history of medullary thyroid carcinoma
- You have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
- You're pregnant, planning to become pregnant, or breastfeeding
- You have a history of pancreatitis
- You're taking other GLP-1 medications (Wegovy, Ozempic, Saxenda)
Not sure if Mounjaro is right for you? Our clinical team will assess your eligibility during your free consultation.
Mounjaro vs Other Weight Loss Medications
See how Mounjaro compares to other leading weight loss treatments.
| Feature | Mounjaro | Wegovy | Saxenda |
|---|---|---|---|
| Active Ingredient | Tirzepatide | Semaglutide | Liraglutide |
| Mechanism | GLP-1 + GIP (Dual) | GLP-1 only | GLP-1 only |
| Frequency | Once weekly | Once weekly | Daily |
| Avg. Weight Loss | Up to 22.5% | Up to 15% | Up to 8% |
| Starting Price (TLWLC) | £194/month | £119/month | £185/month |
Mounjaro Treatment Plans
Start with a single month or save with our 3-month plan. All plans include free delivery and clinical support.
1 Month Supply
Try Mounjaro with no commitment. Perfect if you're new to GLP-1 treatment.
From £214
Starting dose (2.5mg)
- Single month supply
- No commitment required
- Reorder when you need more
3 Month Plan
Save £10/month with our most popular plan. Includes dose titration.
From £612
£204/month (save £10/month)
- 3 months medication supply
- Dose titration included
- Save £30+ vs monthly
💡 Your dose usually increases monthly as part of your titration. Our assessment will recommend the right starting point for you.
Full Mounjaro Pricing by Dose
| Dosage | 1 Month | 3 Month (per month) |
|---|---|---|
| 2.5mg (Starting) | £214 | £204(save £10) |
| 5mg | £244 | £234(save £10) |
| 7.5mg | £294 | £284(save £10) |
| 10mg | £324 | £314(save £10) |
| 12.5mg | £344 | £334(save £10) |
| 15mg (Max) | £359 | £349(save £10) |
Free assessment • Results in minutes • No obligation
Mounjaro Dosing Schedule
Mounjaro uses a gradual dose escalation to minimise side effects and allow your body to adjust.
*Dose escalation may be adjusted by your clinician based on your response and tolerability
Side Effects & Safety
Common Side Effects
These typically improve as your body adjusts (usually within a few weeks):
- Nausea
- Diarrhoea
- Constipation
- Stomach pain/discomfort
- Decreased appetite
- Vomiting
- Indigestion
When to Seek Medical Attention
Contact your doctor or our clinical team immediately if you experience:
- Severe stomach pain that won't go away
- Signs of pancreatitis
- Vision changes
- Severe allergic reaction
- Symptoms of low blood sugar
- Kidney problems (reduced urination)
24/7 Clinical Support at TLWLC
Our clinical team is available around the clock to answer questions and address any concerns about side effects. We monitor your progress throughout your journey and can adjust your treatment plan if needed.
Frequently Asked Questions
Ready to Start Your Weight Loss Journey?
Take the first step. Our free assessment takes just 5 minutes and our clinical team will help determine if Mounjaro is suitable for you. *Subject to programme terms. Individual results vary.