Key Takeaways
- How do the results compare between these two medications?.
- How do the results compare between these two medications?.
- The cost of treatment depends on the provider and plan you choose.
- The active ingredient in a medicine is what makes it work.
Possible Side Effects
- Importantly, Wegovy is the first and only medication currently approved to support both long-term weight management and cardiovascular risk reduction. In the SELECT trial, semaglutide 2.4mg significantly reduced the risk of major adverse cardiovascular events (MACE), including death, heart attack, and stroke, by 20% compared to placebo. This makes it a particularly strong option for people with obesity and existing cardiovascular risk.
- While tirzepatide is not currently approved to reduce the risk of major adverse cardiovascular events (MACE), an ongoing cardiovascular outcomes trial (SURPASS-CVOT) is investigating this, with results expected soon.
- Mounjaro side effects and Wegovy side effects are similar. Most people experience digestive symptoms, especially in the early weeks, which are usually mild to moderate and tend to ease over time. Below are examples of some of side effects you may experience:
- ## Very common side effects (more than 1 in 10 people)
- ## Common side effects (up to 1 in 10 people)
- The 7.2mg dose of Wegovy (its highest dose) has a well-tolerated safety profile, with gastrointestinal symptoms consistent with the GLP-1 class. In clinical trials, 5.4% of participants discontinued due to side effects, lower than the 4% on the 2.4mg dose.
Contact your healthcare provider if you experience any concerning symptoms.
Practical Tips
- →They're not recommended for everyone—you shouldn’t take them if you have type 1 diabetes, inflammatory bowel disease, severe liver or kidney issues, or if you’re pregnant, breastfeeding, or trying to conceive.
- →If you're considering switching, speak to a clinician to discuss the best dose for you and how to transition safely. A one-week gap between medications is usually enough. Our clinical team can recommend the appropriate starting dose, based on your treatment history and experience.
- →While manufacturers recommend starting at the lowest dose, in some cases, starting higher may help you avoid unnecessary setbacks, especially if you’ve built up tolerance. At Voy, we take a personalised approach to help you stay on track.
Start Your Weight Loss Journey Today
Get personalised medical support from our expert team. Book your consultation now.
Dr. Rabih Wassel
Chief Medical Officer • MBBS, BSc, MSc, MRCS, MRCGP
Dr. Rabih Wassel is a board-certified physician specializing in obesity medicine with over 15 years of experience in weight management and metabolic health.
GLP-1 Medications
Obesity Medicine
Metabolic Health