Wegovy Doses for Weight Loss: Complete Titration Guide

Wegovy (semaglutide 2.4mg) follows a carefully designed titration schedule that gradually increases your dose over 16-20 weeks. This slow escalation minimises side effects like nausea while allowing your body to adjust to the medication. Understanding this dosing journey is crucial for maximising weight loss results and staying comfortable throughout treatment.

Understanding Wegovy Dosing

Wegovy is administered as a once-weekly subcutaneous injection. Unlike some medications where you start at the full dose immediately, Wegovy uses a gradual dose escalation approach to:

Reduce gastrointestinal side effects (nausea, vomiting, diarrhoea)
Allow your body to adapt to the medication's effects
Identify the lowest effective dose for each individual
Improve treatment adherence and long-term success

The Titration Schedule Explained

Weeks	Dose	What to Expect
1-4	0.25mg	Minimal side effects, appetite begins to reduce
5-8	0.5mg	Appetite suppression increases, initial weight loss
9-12	1mg	Steady weight loss, fullness after meals
13-16	1.7mg	Accelerated weight loss, sustained appetite control
17+	2.4mg	Maintenance dose, maximum weight loss effect

Maintenance Dose and Long-term Use

The 2.4mg weekly dose is the approved maintenance dose for Wegovy. Most patients remain on this dose for the duration of their weight loss journey and beyond. Key points:

Continue 2.4mg weekly as long as you're tolerating it well and seeing benefits
Weight loss typically continues for 68+ weeks on the maintenance dose
Some patients may benefit from staying on Wegovy long-term to maintain weight loss
Your doctor may adjust the dose based on your individual response and tolerability

What to Do If You Miss a Dose

Missed Dose Guidelines

If less than 2 days have passed:

Take the missed dose as soon as you remember
Resume your regular schedule the following week

If more than 2 days have passed:

Skip the missed dose entirely
Take your next dose on the regularly scheduled day
Do NOT double up to make up for a missed dose

Adjusting Doses Based on Response

Your doctor may modify your Wegovy dose based on:

Side effects: If you experience intolerable nausea or vomiting, your doctor may delay dose escalation
Weight loss response: Some patients achieve excellent results at doses lower than 2.4mg
Medical history: Certain conditions may warrant dose adjustments
Individual tolerance: Not everyone needs or tolerates the maximum dose

Get Expert Guidance on Wegovy Dosing

Our experienced medical team provides personalised dosing plans, ongoing monitoring, and support to help you achieve the best possible results with Wegovy.